Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia

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Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia.

Acute lymphoblastic leukemia (ALL) is the most common form of cancer in children. Recent advances in treatment have led to dramatically improved survival rates. Standard ALL treatment includes multiple administrations of the chemotherapeutic drug vincristine, which is a known neurotoxic agent. Although peripheral neuropathy is a well-known toxicity among children receiving vincristine acutely, ...

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Evaluation of bone mineral density in long-term survivors of childhood acute lymphoblastic leukemia

Background: The purpose of this study was to evaluate long-term changes in bone density profile among survivors of childhood acute lymphoblastic leukemia. Patients and Methods: This was a 5 year prospective study comprised of thirty-one survivors of childhood acute lymphoblastic leukemia with a mean age of 11.8 (4.6) years, who completed therapy at least 1 year previously (according to the ...

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REPORTS Smoking in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Background: Health-related behaviors are of particular concern in survivors of childhood cancer as they are at increased risk for second cancers and long-term organ dysfunction. The purpose of this study was to compare the smoking behavior and associated factors in young-adult survivors of childhood acute lymphoblastic leukemia (ALL) with those in sibling controls. Methods: A telephone intervie...

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STUDY OBJECTIVES To evaluate lung function in patients cured from childhood acute lymphoblastic leukemia (ALL) with chemotherapy alone or plus bone marrow transplantation (BMT). Pulmonary toxicity is a well-recognized side effect of many ALL treatments. DESIGN Cross-sectional study conducted at least 3 years after cessation of therapy. SETTING Outpatient pneumology department of the Univers...

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ژورنال

عنوان ژورنال: Journal of the Peripheral Nervous System

سال: 2009

ISSN: 1085-9489,1529-8027

DOI: 10.1111/j.1529-8027.2009.00230.x